Scientists from the Russian National University of Science and Technology MISIS (NUST MISIS) have created new biodegradable, living bandage. The new therapeutic material consists of nanofibers made from polycaprolactone, and modified with antibacterial films (including silver nanoparticles) and plasma components of human blood. The blood plasma components (growth factors, fibrinogens, and other proteins) help to promote cell growth, while the antibacterial films keep wounds clean and decrease inflammation. The group envisions that the bandages will not need to be removed during treatment, but rather the biodegradable fiber will ‘dissolve’.
In pre-clinical trials in conjunction with the Research Institute of Experimental and Clinical Medicine (Novosibirsk, Russia), the scientists found that the living bandages can help increase the rejuvenation of skin cells by doubling the growth of cells compared to conventional bandages; however, results to date have only been demonstrated in vitro.